LEVERAGING THE POWER OF NATURE FOR SUSTAINABLE CHEMICAL SYNTHESIS
How can biocatalysis make the manufacturing of value-added chemical products more efficient and sustainable, cheaper and cleaner? We provide experimental data that helps manufacturing companies to implement biocatalytic cascades in their production plants. Thereby, we contribute to the transition toward a greener chemical production.
STATE OF THE ART
In traditional chemical synthesis non-compatible reactions are carried out separately. This is time consuming, inefficient and infers high costs due to intermediate purification.
METABOLIC ENGINEERING OF MICROBES
Live microbes with artificially designed metabolic pathways produce chemicals through a series of enzyme-catalyzed reactions from renewable feedstocks. Such systems are difficult to optimize and only yield low product titers.
IN VITRO BIOCASCADES
The benefits of chemical synthesis and metabolic engineering combined. No living cells are needed. Compatible biocatalysts (enzymes) operate together in a single reaction vessel with high substrate loadings, selectivity and under mild reaction conditions.
WHAT WE DO...
CASCADE DEVELOPMENT AND OPTIMIZATION
We identify an ensemble of biocatalysts that could deliver a desired value-added product from preferably renewable starting materials. Furthermore, we find the conditions under which the biocatalysts optimally work together and yield the highest product quality and quantity.
Can an enzyme or protein of interest be produced in a microbial host organism? How could the heterologous expression be optimized? Is the biocatalyst able to convert a given substrate into the desired product(s)? These and more questions are addressed in our enzyme characterization service.
Biocatalysis is perfectly suited to transform substrates from renewable resources to value-added chemical products
Pharmaceuticals and APIs
Beverage- and food additives
Fragrance- and flavor compounds
Our interdisciplinary team combines a strong scientific background in the fields of biocatalysis, biotechnology and organic chemistry with entrepreneurial experience.
Dr. Stefan Payer (Chemist, CEO)
Dr. Mattia Lazzarotto (Chemist, CSO)
Dr. Mathias Pickl-Farnberger (Chemist)
Dr. Elisa Lanfranchi (Biotechnologist)
Prof. Dr. Wolfgang Kroutil (Scientific advisor)
Stefan Steinberger (Partnerships)
We are a spinoff of
Vast experience and know-how in chemistry and biocatalysis
Diverse biocatalyst library
Modern analytical instruments
Liquid-handling robot for high-throughput experimentation
AI-assisted cascade optimization
Funded through Preseed – Deep Tech by the Austrian BMAW and BMK executed by aws