We’re rewriting chemistry with the language of nature using enzymes for simpler, safer, and cost-effective access to small molecules.

Enzymes are...

… nature’s molecular machines: diverse, efficient, and refined over millions of years of evolution. Their vast variety enables countless reactions, many beyond the reach of traditional chemistry. With advances in molecular biology, enzymes can now be engineered for entirely new functions, tailored to specific processes.

In nature, enzymes operate in precise networks to build complex molecules with minimal waste. By combining them in streamlined, cell-free systems, we can replicate this efficiency while fine-tuning each step. This approach unites the best of both worlds: the flexibility of organic synthesis with the efficiency and sustainability of biology.

Highlights from past projects

Proof-of-concept for new-to-nature reaction

From zero to one in two months. We screened a set of potential biocatalysts and identified reaction conditions to establish a yet unknown biotransformation. Our contribution allowed our customer to de-risk their endeavor and quickly move on to the next product development step.

Cascade development

Finding a new-to-nature combination of five enzymes to transform a starting material into the desired API product in a one-pot setup. In four months we could establish a proof of concept and determine the substrate scope of the cascade. The data was used for a successful patent application.

Enzyme engineering

By following a semi-rational engineering approach based on the enzyme structure, we achieved a 25-fold activity improvement for a target reaction within four months. The improved variants will form the basis of a platform manufacturing technology in the life-sciences field.

Proof-of-concept for new-to-nature reaction

Cascade development

Enzyme engineering